The laboratory is part of the care team—not a hidden back room.
VCRM provides in-house embryology, andrology and reproductive hormone testing. The laboratory pathway also includes selective sperm DNA fragmentation testing when it may add useful information beyond a standard semen analysis.
Personalized Care
Every cycle is managed directly by Dr. Sharara with dedicated one-on-one monitoring.
Schedule Visit (703) 437-7722ZyMōt™ ICSI Sperm Separation Device at VCRM
Since July 2022, VCRM has migrated to using the new ZyMōt™ sperm separation device for all IVF cases. The ZyMōt device simulates the natural micro-barriers of the cervical and uterine pathways that sperm must overcome in natural conception, allowing separation of optimally functional sperm without the use of damaging chemicals or density gradient centrifugation.
ZyMōt ICSI sperm separation devices isolate sperm with near-zero DNA fragmentation and significantly lower oxidative stress compared to traditional centrifugation. Recent studies demonstrate a higher fertilization rate and a higher number of euploid (genetically normal) embryos.
In a landmark clinical study of over 3,600 oocytes (The Fertility & IVF Center of Miami), researchers observed a significant increase in fertilization rates—rising from 75% using traditional sperm preparation methods to 83% using ZyMōt devices (an 11% increase, p < 0.05).
In-House Embryology Services
Our state-of-the-art embryology laboratory performs all advanced IVF procedures in-house under strict quality control led by Lab Director Dr. Chad A. Johnson, PhD, HCLD and Dr. Fady Sharara:
- Intracytoplasmic Sperm Injection (ICSI): Single sperm microinjection into eggs for male-factor infertility or fertilization optimization.
- Day 5 Blastocyst Culture: Extended embryo culture to Day 5, achieving maximum implantation potential before transfer.
- Preimplantation Genetic Testing (PGT): Biopsy of blastocysts for PGT-A (chromosome screening) and PGT-M (single-gene disorder screening).
- Assisted Hatching: Micromanipulation to assist embryo hatching prior to transfer.
- Vitrification & Cryopreservation: Ultra-rapid freezing of eggs and blastocysts for future use.
In-House Andrology & Sperm Function Testing
Comprehensive male fertility diagnostic and therapeutic services:
- Standard Semen Analysis: Volume, sperm concentration, motility, and strict morphology evaluation.
- Sperm DNA Fragmentation Testing (Halo/DFI): Assesses genetic integrity and strand breaks to identify hidden male factor causes in unexplained infertility and recurrent pregnancy loss.
- Sperm Washing & Preparation: Customized preparation for IUI and IVF procedures.
In-House Reproductive Hormone Analysis
Rapid, same-day blood analysis for reproductive hormones (Estradiol, Progesterone, LH, FSH, AMH, hCG). In-house endocrine testing allows Dr. Sharara to adjust stimulation medication doses immediately during cycle monitoring.
Frequently Asked Laboratory Questions
What is ZyMōt sperm separation?
ZyMōt is a microfluidic device that selects healthier, motile sperm with near-zero DNA fragmentation without centrifugation, improving IVF fertilization rates by 11%.
What is ICSI?
Intracytoplasmic sperm injection is a laboratory fertilization technique where a single optimal sperm is directly microinjected into an egg.
What is blastocyst culture?
Culture of embryos to Day 5 (blastocyst stage) allows optimal selection of robust embryos with highest implantation potential.
Sperm DNA Fragmentation Testing
Advanced Sperm DNA Fragmentation analysis assesses genetic integrity and chromatin damage that standard semen analysis cannot detect. Elevated DNA fragmentation (DFI > 25–30%) is a leading cause of unexplained infertility, failed IUI cycles, embryo arrest, and recurrent miscarriage.
Testing empowers Dr. Sharara to customize treatment pathways—such as utilizing ZyMōt microfluidic sperm separation to isolate sperm with near-zero DNA fragmentation for ICSI, significantly improving embryo quality and fertilization rates.
Experience State-of-the-Art Laboratory Care
Learn more about how VCRM’s advanced in-house lab, ZyMōt technology, and 1:1 physician oversight maximize your pregnancy success.
Personalized Care
Every cycle is managed directly by Dr. Sharara with dedicated one-on-one monitoring.
Schedule Visit (703) 437-7722